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Does VIMPAT cause heart problems?

Does VIMPAT cause heart problems?

VIMPAT may cause you to have an irregular heartbeat or may cause you to faint. In rare cases, cardiac arrest has been reported. Call your healthcare provider right away if you: have a fast, slow, or pounding heartbeat or feel your heart skip a beat.

Can VIMPAT cause bradycardia?

Intravenous infusion of VIMPAT may cause bradycardia, AV blocks, and ventricular tachyarrhythmia [see Warnings and Precautions (5.3)].

Can lacosamide cause bradycardia?

The most serious adverse effects reported with lacosamide are cardiac con- duction disturbances (Degiorgio, 2010; Nizam et al., 2011). We report a case of sinus node dysfunction associated with lacosamide therapy leading to recurrent transient episodes of asystole and sinus bradycardia.

Does Vimpat lower your immune system?

This medication may rarely cause a serious immune system problem (Drug Reaction with Eosinophilia and Systemic Symptoms).

Do seizures weaken your heart?

The electrical activity in the brain during a seizure can also change our pulse and usually causes an increase in heart rate. However, during some seizures, the heart can slow or even stop temporarily, which is referred to as ictal asystole.

What heart conditions cause seizures?

Diseases causing cardiac enlargement such as hypertension, valve disease, dilated cardiomyopathy or hypertrophic cardiomyopathy can also trigger arrhythmias. All of these as well as congenital arrhythmic processes have the potential to present with seizure activity.

What drugs should not be taken with Vimpat?

VIMPAT should also be used with caution in patients on concomitant medications that affect cardiac conduction, including sodium channel blockers, beta-blockers, calcium channel blockers, potassium channel blockers, and medications that prolong the PR interval.

What are the long term side effects of Vimpat?

Common side effects of Vimpat include: blurred vision, diplopia, dizziness, fatigue, headache, nausea, nystagmus disorder, tremor, vomiting, and ataxia. Other side effects include: abnormal gait, asthenia, memory impairment, and vertigo. See below for a comprehensive list of adverse effects.

What’s the difference between Vimpat and Lacosamide?

Lacosamide. Lacosamide (la-COS-a-mide) is the generic name (non-brand name) for the brand drug called Vimpat (VIM-pat) from UCB. It is available in tablet form, a liquid solution, and a liquid for injection. Lacosamide is available in many countries, but the name or look may be different. The dose measured in milligrams (mg) is the same.

Why is Vimpat considered a C-V drug?

4. VIMPAT is a federally controlled substance (C-V) because it can be abused or lead to drug dependence. Keep your VIMPAT in a safe place, to protect it from theft. Never give your VIMPAT to anyone else, because it may harm them.

Why did my son stop taking Vimpat after 2 months?

Our son got heartproblems.He was very ill and fortunately he, after two months, was operated, cryoablation. Of course he has stopped taking Vimpat because of danger with his heart.I want to warn everyone before starting with this medicin! Our son got heartproblems.He was very ill and fortunately he, after two months, was operated, cryoablation.

Common side effects of Vimpat include: blurred vision, diplopia, dizziness, fatigue, headache, nausea, nystagmus disorder, tremor, vomiting, and ataxia. Other side effects include: abnormal gait, asthenia, memory impairment, and vertigo. See below for a comprehensive list of adverse effects.

What’s the half life of Vimpat compared to Lacosamide?

Pharmacokinetics of VIMPAT are dose proportional (100-800 mg) and time invariant, with low inter- and intra-subject variability. Compared to lacosamide the major metabolite, O-desmethyl metabolite, has a longer Tmax (0.5 to 12 hours) and elimination half-life (15-23 hours). VIMPAT is completely absorbed after oral administration.

4. VIMPAT is a federally controlled substance (C-V) because it can be abused or lead to drug dependence. Keep your VIMPAT in a safe place, to protect it from theft. Never give your VIMPAT to anyone else, because it may harm them.

How is the bioavailability of Vimpat tablets determined?

The oral bioavailability of VIMPAT tablets is approximately 100%. Food does not affect the rate and extent of absorption. After intravenous administration, Cmax is reached at the end of infusion. The 30- and 60-minute intravenous infusions are bioequivalent to the oral tablet.