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How long should clopidogrel be given along with aspirin after angioplasty and drug-eluting stent placement?

How long should clopidogrel be given along with aspirin after angioplasty and drug-eluting stent placement?

Conclusions: The combination of clopidogrel (loading dose, 300-600 mg; maintenance dose, 75 mg/d) and low-dose aspirin (75-162 mg/d) for 12 months is the preferred regimen for the prevention of stent thrombosis and cardiac complications after DES placement.

How long should I take my Plavix after stenting?

Patients with stable coronary disease: Plavix combined with aspirin, called dual anti-platelet therapy or DAPT, reduce the risk of stent thrombosis which can result in myocardial infarction and death. After implantation of a bare metal stent, the risk of stent thrombosis is highest in the 1st few days to weeks after implant.

Which is better for stenting aspirin or Plavix?

Multi center trials clearly demonstrated the benefit of using dual anti-platelet (DAPT) consisting of aspirin and Plavix as superior to Coumadin or aspirin alone. We currently follow a patient who underwent coronary stenting of the circumflex coronary artery in the early 90s using the femoral approach.

Which is longer DAPT or Plavix after stent?

The conundrum of increasing duration of DAPT faced by the panelists and the cardiology community is best summed up in this exchange between panelist Dr. Chris White of the Ochsner Clinic and chairperson Dr. William Maisel: DR. WHITE: I’m loath to change the recommendations that were made without evidence, compelling evidence to make us change.

Is there a trial between aspirin and clopidogrel?

The HOST-EXAM is the first randomised trial to compare clopidogrel and aspirin monotherapy in patients who received percutaneous coronary intervention with a drug-eluting stent.

When to start clopidogrel therapy after stent placement?

Clopidogrel therapy is mandatory for six weeks after placement of bare-metal stents, three to six months after myocardial infarction, and at least 12 months after placement of drug-eluting stents.

When to stop taking aspirin after a stent?

Now, new research suggests these patients can safely drop the aspirin regimen after just three months, and lower their bleeding risk in the process.

Can a stent be treated with two antiplatelet drugs?

Following stent insertion, patients with an indication for anticoagulation have been treated with two antiplatelet drugs and an anticoagulant. Recent research suggests that selected patients may be managed with one antiplatelet drug and an anticoagulant.

The HOST-EXAM is the first randomised trial to compare clopidogrel and aspirin monotherapy in patients who received percutaneous coronary intervention with a drug-eluting stent.