Users' questions

What are the long-term effects of fluoxetine?

What are the long-term effects of fluoxetine?

My question is about the long-term effects of fluoxetine. I have been feeling extremely sleepy and lethargic for the past five years or so. I never seem to get enough sleep to feel rested. I wonder if the lack of energy and sluggishness might be a side-effect of being on the medication for 20+ years. Hi, sunrise!

When was fluoxetine first used in the US?

Fluoxetine was discovered by Eli Lilly and Company in 1972, and entered medical use in 1986. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication.

How much fluoxetine is in the human body?

Blood or plasma fluoxetine concentrations are usually in a range of 50–500 μg/L in persons taking the drug for its antidepressant effects, 900–3000 μg/L in survivors of acute overdosage and 1000–7000 μg/L in victims of fatal overdosage.

How is fluoxetine used in the treatment of OCD?

It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. It may decrease the risk of suicide in those over the age of 65. It has also been used to treat premature ejaculation. Fluoxetine is taken by mouth.

How long have I been on Prozac and fluoxetine?

Prozac (fluoxetine): “I’ve been on Prozac for 5 months. Started with 20 MG, 40 MG, and currently on 60 MG. I’ve had severe anxiety and a depressive episode during my pregnancy. I had my son in December. I thought I would feel better once I wasn’t pregnant anymore. I still feel anxious, and depressed, but Prozac has caused me to feel numb.

My question is about the long-term effects of fluoxetine. I have been feeling extremely sleepy and lethargic for the past five years or so. I never seem to get enough sleep to feel rested. I wonder if the lack of energy and sluggishness might be a side-effect of being on the medication for 20+ years. Hi, sunrise!

How many milligrams of fluoxetine does it take?

The patient’s prescribed medications were fluoxetine 20 mg daily and buspirone 15 mg twice daily. The patient stated that she had taken her buspirone only as directed, with the last dose on the morning of the fluoxetine overdose, about six hours earlier. She specifically denied ingesting any additional buspirone or any other medications.

When did I stop crying after taking fluoxetine?

About two or three weeks into my treatment with fluoxetine, I noticed that I no longer began to cry when faced with things that usually sent me into fits of tears. This side effect lasted for several months before I could cry again. I think I still cry less often than before I started taking fluoxetine, however.

How long does it take to taper off Prozac?

Tapering may not be necessary with Prozac due to the long half-life. I have been on 30mg of Prozac for two weeks, I was increased from 20 to 30. I felt good for ten days, but then became very tired. We are dropping back down to 20 mg. How long will it take for me to get back down to 20 mg?

Is there a way to taper off Lexapro?

If you experience discontinuation symptoms after a particular dose reduction, you may want to add back half the dose — or all of it — and continue from there with smaller dose reductions. There are no hard and fast rules for getting off antidepressants, other than that the approach should be individualized!

What happens when you discontinue an extended release antidepressant?

Extended-release versions of these drugs enter the body more slowly but leave it just as fast. Antidepressants with a longer half-life, chiefly fluoxetine, cause fewer problems on discontinuation. Besides easing the transition, tapering the dose decreases the risk that depression will recur.