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What are the symptoms of panhypopituitarism in children?

What are the symptoms of panhypopituitarism in children?

As a child of 6, he’d undergone surgery and radiation therapy to treat a malignant anterior pituitary gland tumor. This resulted in a deficiency of all anterior pituitary gland hormones. Called panhypopituitarism, this disorder includes deficiencies in growth hormone, thyroid-stimulating hormone, and adrenocorticotropic hormone.

Where does panhypopituitarism occur in the human body?

Panhypopituitarism is a condition in which the production and secretion of all hormones by the pituitary gland is reduced. The pituitary gland, also called the “master gland of the body”, is a pea-sized organ located in the center of the brain. It produces and regulates the release of many different chemicals,…

How many people are affected by hypopituitarism in the US?

Hypopituitarism refers to decreased secretion of one, a few (isolated or partial hypopituitarism), or all the anterior pituitary hormones, which is known as panhypopituitarism. 1,2 A rare disorder, panhypopituitarism affects fewer than 200,000 patients in the United States according to the National Institutes of Health. 3

Why is LR at risk for panhypopituitarism?

The excision of a pituitary tumor and radiation therapy placed LR at risk for panhypopituitarism due to damage of the pituitary gland and resulting deficiency of anterior pituitary hormones.

What are the acquired causes of panhypopituitarism?

Acquired panhypopituitarism can occur as a result of tumors in the pituitary gland. It can also arise due to head injuries, radiation treatment, autoimmune conditions, stroke, brain infections, or brain surgery. Pituitary dwarfism is dwarfism caused by a lack of growth hormone, usually due to malfunction of the pituitary gland.

How is panhypopituitarism diagnosed?

How is Panhypopituitarism diagnosed? The diagnosis of hypopituitarism is made by measuring basal hormone levels in the morning fasting status or performing stimulation tests if necessary.

What is the pathophysiology of panhypopituitarism?

Hypopituitarism is a health condition characterized by the reduced production of hormones from the pituitary gland. The pathophysiology of hypopituitarism usually involves damage to the pituitary gland, which renders it unable to produce one or more hormones in the normal manner.