Users' questions

When was lithium medication discovered?

When was lithium medication discovered?

The breakthrough in lithium treatment for mania and the prophylaxis of manic-depressive illness began in 1952, when Erik Strömgren, head of the Aarhus University psychiatric clinic in Risskov, Denmark—who had read the Cade article—suggested to a staff psychiatrist at the hospital, Mogens Schou, that he might undertake …

When was the first case of bipolar disorder diagnosed?

The third edition of the DSM, published in 1980, was the first time bipolar disorder was identified as such. It was also the first appearance of modern criteria for defining the mood disorder, and the first time it was separated as a condition from generalized depression.

Who first discovered lithium?

Johan August Arfwedson
Lithium/Discoverers

Lithium is rare in the Universe, although it was one of the three elements, along with hydrogen and helium, to be created in the Big Bang. The element was discovered on Earth in 1817 by Johan August Arfvedson (1792-1841) in Stockholm when he investigated petalite, one of the first lithium minerals to be discovered.

Who discovered lithium for mental illness?

Some 70 years ago, John Cade, an Australian psychiatrist, discovered a medication for bipolar disorder that helped many patients to regain stability swiftly. Lithium is now the standard treatment for the condition, and one of the most consistently effective medicines in psychiatry.

When was lithium first discovered as a drug for mental health?

When was lithium first discovered as a drug for mental health, and what is the history of this medication? How does it actually work? And what is the current thought and controversy considering the role of lithium in the treatment of bipolar disease?

When to use lithium first line for bipolar disorder?

In the U.S., lithium is seldom used first-line for people with bipolar disorder, though it is still frequently used for severe bipolar disorder in combination with other medications. A 2017 study did, however, suggest that there is a strong role for lithium first line in the treatment of mania in the elderly.

Where was lithium found on the periodic table?

Lithium is a naturally occurring element (number three on the periodic table) that was first discovered in 1817 and was found in mines in Australia and Chili. Its mood-stabilizing effects, however, were not recognized until late in that century. In fact, some concluded that gout was the cause of mood disorders.

How many babies have cardiac malformations from lithium?

Cardiac malformations were present in 16 of the 663 infants exposed to lithium (2.41%), 15,251 of the 1,322,955 nonexposed infants (1.15%), and 27 of the 1945 infants exposed to lamotrigine (1.39%).

When was lithium first discovered as a drug for mental health, and what is the history of this medication? How does it actually work? And what is the current thought and controversy considering the role of lithium in the treatment of bipolar disease?

When did Sir Alfred Baring Garrod discover lithium?

About 40 years later, in 1859, Sir Alfred Baring Garrod discovered that one formed a great deal of uric acid crystals in gout. In his book The Nature and Treatment of Gout and Rheumatic Gout he considered the use of lithium salts as making the uric acid crystals go into solution.

When did lithium first become popular in Europe?

Lithium became and remained popular in Europe and finally in 1974, lithium was approved for the prevention of recurrent mania. The initial doses Cade proposed are more or less the doses still used, though a clearer therapeutic range is understood, and monitoring of dosage levels is important and routine.

When to tell your doctor if you have lithium toxicity?

Tell your doctor if you take lithium and notice any of the following side effects: These side effects can happen with low doses of lithium and don’t mean you have lithium toxicity. However, they may be a sign that you need to adjust your dosage or need more frequent monitoring. What causes lithium toxicity?