Popular guidelines

Why are patients given hydralazine?

Why are patients given hydralazine?

Hydralazine is used to treat high blood pressure. Hydralazine is in a class of medications called vasodilators. It works by relaxing the blood vessels so that blood can flow more easily through the body.

Why do we give hydralazine slowly?

Initially 5 to 10 mg by slow intravenous injection, to avoid precipitous decreases in arterial pressure with a critical reduction in cerebral or utero-placental perfusion. If necessary a repeat injection can be given after an interval of 20-30 minutes, throughout which blood pressure and heart rate should be monitored.

Can hydralazine be stopped suddenly?

Don’t stop taking hydralazine suddenly. Doing so may lead to uncontrolled high blood pressure. It can raise your risk for heart problems, such as chest pain or heart attack. If you need to stop taking this drug, your doctor will slowly lower your dose over two weeks.

Can hydralazine make you sleepy?

Hydralazine oral tablet doesn’t cause drowsiness, but it can cause other side effects.

When to tell your doctor about hydralazine side effects?

To make sure hydralazine is safe for you, tell your doctor if you have ever had: a stroke. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Hydralazine can pass into breast milk, but effects on the nursing baby are not known.

What is the cerebral hemodynamic effect of hydralazine?

Abstract. Hydralazine is shown to have a very complex cerebral hemodynamic effect. It raises the intracranial pressure which, together with its effect upon systemic blood pressure, reduces the cerebral perfusion pressure. In spite of this and a concomitantly induced hyperventilation by hydralazine, CBF increases with some delay.

What kind of injection is hydralazine hydrochloride injection?

Hydralazine Hydrochloride Injection, USP is an antihypertensive available in a 1 mL vial for intravenous and intramuscular administration. Hydralazine Hydrochloride Injection, USP is a sterile, nonpyrogenic colorless solution.

What are the preservatives and active ingredients of hydralazine?

Active: Hydralazine Hydrochloride USP, 20 mg. Preservatives: Methylparaben NF, 0.65 mg; Propylparaben NF, 0.35 mg. Inactives: Propylene Glycol USP, 103.6 mg; Sodium Hydroxide and/or Hydrochloric Acid USP to adjust pH (3.4 to 4.4) and Water for Injection.

How to stop taking hydralazine?

Do not use this medicine in larger or smaller amounts or for longer than recommended. You should not stop using hydralazine and isosorbide dinitrate suddenly. Stopping suddenly may make your condition worse. Store at room temperature away from moisture, heat, and light.

How should I take hydralazine?

Hydralazine can be taken orally; it can be injected or administered through an intravenous drip. If taken orally – usually two to four times a day – it should be taken with food.

What are the side effects of hydralazine?

Hydralazine is an oral and injectable drug that’s used to treat high blood pressure. It’s used alone or in combination with other blood pressure-lowering drugs. Common side effects include headache, loss of appetite, nausea, vomiting, diarrhea, fast heart rate, and chest pain. Don’t stop taking hydralazine suddenly.

Does hydralazine decrease heart rate?

The peripheral vasodilating effect of Hydralazine results in decreased arterial blood pressure (diastolic more than systolic), decreased peripheral vascular resistance, and an increased heart rate, stroke volume, and cardiac output. The preferential dilatation of arterioles , as compared to veins,…