Users' questions

Why do we use hydroxychloroquine to treat SLE?

Why do we use hydroxychloroquine to treat SLE?

HCQ may reduce the risk of flares, allow the reduction of the dosage of steroids, reduce organ damage, and prevent the thrombotic effects of anti-phospholipid antibodies. The drug is generally safe and may be prescribed to pregnant women.

What is the impact of hydroxychloroquine on patients with SLE?

In patients with systemic lupus erythematosus (SLE), hydroxychloroquine prevents disease flares and damage accrual and facilitates the response to mycophenolate mofetil in those with renal involvement. A study was undertaken to determine whether hydroxychloroquine also exerts a protective effect on survival.

Is hydroxychloroquine used for lupus and malaria?

Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine (Aralen) and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis.

What benefits does hydroxychloroquine have for treatment of symptoms of lupus?

Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate.

When should you not take hydroxychloroquine?

low blood sugar. glucose-6-phosphate dehydrogenase (G6PD) deficiency. low amount of magnesium in the blood. low amount of potassium in the blood.

How is hydroxychloroquine used to treat systemic lupus?

Hydroxychloroquine in systemic lupus erythematosus (SLE) Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus (SLE).

How is HCQ used in the treatment of SLE?

Areas covered: In this review the mechanisms of action, the efficacy, and the safety of HCQ in the management of patients with SLE have been reviewed. HCQ may reduce the risk of flares, allow the reduction of the dosage of steroids, reduce organ damage, and prevent the thrombotic effects of anti-phospholipid antibodies.

Where can I get hydroxychloroquine for SLE?

1 a Nephrological Unit , Humanitas Clinical and Research Center , Rozzano (Milano) , Italy. 2 b Nephrological Unit , Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico , Milan , Italy.

How is hydroxychloroquine used in autoimmune disease?

Abstract Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus (SLE).

How is hydroxychloroquine used in the treatment of lupus?

Hydroxychloroquine: a multifaceted treatment in lupus The efficacy of antimalarials, especially hydroxychloroquine (HCQ), in preventing systemic lupus erythematosus (SLE) flares is well demonstrated. However, many studies show that the percentage of SLE patients treated with HCQ remains low.

1 a Nephrological Unit , Humanitas Clinical and Research Center , Rozzano (Milano) , Italy. 2 b Nephrological Unit , Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico , Milan , Italy.

Areas covered: In this review the mechanisms of action, the efficacy, and the safety of HCQ in the management of patients with SLE have been reviewed. HCQ may reduce the risk of flares, allow the reduction of the dosage of steroids, reduce organ damage, and prevent the thrombotic effects of anti-phospholipid antibodies.

Abstract Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus (SLE).